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Milwaukee Section - American Chemical Society the amalgamator |
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Milwaukee Section - American Chemical Society the amalgamator |
October 2001 Meeting
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Thursday, October 18, 2001 Fireside Lounge University of Wisconsin-Milwaukee Union Building (second floor) |
DIRECTIONS |
| 6:00 PM | - Social Hour |
| 7:00 PM | - Dinner |
| 8:00 PM | - Program (Bolton Hall, Rm 150) |
Buffet Dinner:
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| Prices include tax and gratuity. | ||
| Members/Guests | .... | $19.00 |
| Chemistry Students | .... | $10.00 |
Catalysts not only accelerate chemical reactions, but can also exert remarkable kinetic control over product distribution. My research group is interested in all aspects of selective catalysis, and especially in the design, discovery, and study of systems that mediate fundamentally interesting and useful organic reactions. The search for practical and widely applicable catalysts for organic synthesis provides a strong driving force for our research. In addition, we apply the tools of physical-organic chemistry to gain insight into the transition structure geometries and molecular recognition events that control selectivity.
The following topics in selective catalysis are currently under investigation in our laboratories:
The control of absolute and relative stereochemistry is an underlying goal in much of this work because of the crucial role played by the three-dimensional structure of molecules in their biological function. The development of enantioselective oxidation catalysts has been of particular interest to us, and we have succeeded in devising highly enantioselective small-molecule catalysts in which selectivity is predicated solely through non-bonded interactions. The utility of these catalysts has been illustrated in our group through their application to the synthesis of various classes of important biologically active compounds.
Eric Jacobsen was born on February 22, 1960 in Manhattan. He was raised in New York City, and he obtained his B.S. degree from NYU in 1982. As an undergraduate, he carried out research in the laboratories of Prof. Yorke Rhodes. His Ph.D. work was done at Berkeley in the field of organometallic chemistry under the direction of Bob Bergman. In 1986, he returned to the East Coast for an NIH postdoctoral fellowship at MIT with Barry Sharpless. In 1988, he began his independent career at the University of Illinois, where he was promoted to associate professor in 1991. He moved to Harvard University as full professor in the summer of 1993, and he was named the Sheldon Emory Professor of Chemistry this year. He currently directs a research group of 22 graduate students and postdocs at Harvard. He is a member of the BOD and SAB of Rhodia ChiRex, and he is also a consultant at Merck, Sepracor, and Versicor.
Eric Jacobsen's research interests lie in the discovery, mechanistic elucidation, and application of new reactions of practical value, with special emphasis on asymmetric catalytic processes. The awards he has received include the NSF Presidential Young Investigator Award (1990), the Packard Fellowship (1991), the Camille and Henry Dreyfus Teacher-Scholar Award (1992), the Alfred P. Sloan Foundation Fellowship (1992), the Cope Scholar Award (1993), the Fluka "Reagent of the Year" Prize (1994), the Thieme-IUPAC Prize in Synthetic Organic Chemistry (1996), the Baekeland Medal (1999), and the ACS Award for Creativity in Synthetic Organic Chemistry (2001).
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